USP2 Antibody

Immunohistochemistry-Paraffin: USP2 Antibody [NB110-40473] - Analysis of anti-USP2 antibody with human skeletal muscle.

Product Discontinued

USP2 Antibody Summary

• Immunogen: Synthetic 19 amino acid peptide from internal region of human USP2.
• Epitope: N-terminal domain of human
• Localization: Cell Membrane
• Specificity: Human USP2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except RC3H2 (42%).
• Predicted Species: Monkey (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: USP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1.3 ug/ml
• Control:

  TRPV6 Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Marmoset (95%), Gibbon (89%), Rabbit (84%), Opossum (84%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 0.9 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for USP2 Antibody

• Deubiquitinating enzyme 2
• EC 3.1.2.15
• EC 3.4.19.12,41 kDa ubiquitin-specific protease
• ubiquitin specific peptidase 2
• ubiquitin specific protease 12
• ubiquitin specific protease 2
• ubiquitin specific protease 9
• ubiquitin thioesterase 2
• Ubiquitin thiolesterase 2
• Ubiquitin-specific-processing protease 2
• UBP41
• UBP41ubiquitin carboxyl-terminal hydrolase 2
• USP2
• USP9

Background

Transient receptor potential vanilloid (TRPV) channels are widely expressed in both sensory and nonsensory cells. TRPV2, a member of transient receptor potential ion channels, responds to high-threshold noxious heat (with a threshold of approximately 52 degrees C), but neither to capsaicin nor to proton. TRPV2 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. It has been proposed that responses to noxious heat involve these related, but distinct, ion-channel subtypes that together detect a range of stimulus intensities.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: USP2
• Entrez:
  • 9099(Human)
• Uniprot:
  • O75604()