Human USP14 ELISA Kit (Colorimetric)

ELISA: Human USP14 ELISA Kit (Colorimetric) [NBP3-38796] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Tissue homogenates and other biological fluids
• Standard Curve Range: 0.312 - 20 ng/mL (example only; lot dependent)
• Sensitivity: 0.108 ng/mL (example only; lot dependent)

Human USP14 ELISA Kit (Colorimetric) Summary

• Description: Assay Length: 4.5 hours
• Standard Curve Range: 0.312 - 20 ng/mL (example only; lot dependent)
• Sensitivity: 0.108 ng/mL (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Inter-Assay: %CV < 12 (example only; lot dependent)
• Intra-Assay: %CV < 10 (example only; lot dependent)
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: USP14

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human USP14 ELISA Kit (Colorimetric)

• Deubiquitinating enzyme 14
• EC 3.1.2.15
• EC 3.4.19.12
• TGT
• TGTubiquitin carboxyl-terminal hydrolase 14
• tRNA-guanine transglycosylase, 60-kD subunit
• ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
• ubiquitin specific protease 14 (tRNA-guanine transglycosylase)
• Ubiquitin Thioesterase 14
• Ubiquitin thiolesterase 14
• ubiquitin-specific processing protease 14
• Ubiquitin-specific-processing protease 14
• Ubp6
• USP14

Background

USP14 encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: USP14