UGRP1/SCGB3A2 Antibody (1B2) - Azide and BSA Free

ELISA: UGRP1/SCGB3A2 Antibody (1B2) [H00117156-M01] - Detection limit for recombinant GST tagged SCGB3A2 is approximately 0.3ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 1B2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

UGRP1/SCGB3A2 Antibody (1B2) - Azide and BSA Free Summary

• Immunogen: SCGB3A2 (AAH24232, 1 a.a. ~ 93 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MKLVTIFLLVTISLCSYSATAFLINKVPLPVDKLAPLPLDNILPFMDPLKLLLKTLGISVEHLVEGLRKCVNELGPEASEAVKKLLEALSHLV
• Localization: Secreted
• Specificity: SCGB3A2 - secretoglobin, family 3A, member 2
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: SCGB3A2
• Purity: Ascites

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Ascites

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for UGRP1/SCGB3A2 Antibody (1B2) - Azide and BSA Free

• LU103
• Pneumo secretory protein 1
• PnSP-1
• PNSP1secretoglobin family 3A member 2
• SCGB3A2
• secretoglobin, family 3A, member 2
• UGRP1
• UGRP1pnSP-1
• Uteroglobin-related protein 1

Background

In addition to regulating thyroid-specific expression of genes, thyroid transcription factor (TITF1; MIM 600635) controls the transcription of genes specifically expressed in lung, such as surfactant proteins (e.g., SFTPA1; MIM 178630) and uteroglobin (UGB; MIM 192020). Mice lacking Ttf1 die immediately after birth from respiratory failure caused by profoundly hypoplastic lungs (Kimura et al., 1996 [PubMed 8557195]). The UGRP1 gene encodes a uteroglobin-related protein and is a downstream target of TITF1.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for UGRP1/SCGB3A2 Antibody (H00117156-M01)(3)

Publications using H00117156-M01

• Shiraishi K, Morley MP, Jones DL et Al. Airway epithelial cell identity and plasticity are constrained by Sox2 during lung homeostasis, tissue regeneration, and in human disease NPJ Regen Med 2024-01-05 [PMID: 38182591]
• Basil MC, Cardenas-Diaz FL, Kathiriya JJ et al. Human distal airways contain a multipotent secretory cell that can regenerate alveoli Nature 2022-04-07 [PMID: 35355013]
• Van De Velde V, Courtens W, Bernard A. Development of a new sensitive ELISA for the determination of uteroglobin-related protein 1, a new potential biomarker. Biomarkers. 2010-09-15 [PMID: 20843168]

Bioinformatics

• Gene Symbol: SCGB3A2
• Entrez:
  • 117156(Human)
• OMIM:
  • 600807(Human)
• Uniprot:
  • AAH24232(Human)