UFD1L Antibody (5e2)

Product Discontinued

UFD1L Antibody (5e2) Summary

• Immunogen: Full length mouse Ufd1 expressed in E. coli
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: UFD1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunocytochemistry/ Immunofluorescence 5 ug/ml
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1:100 - 1:2000
• Application Notes: Positive control(s): HeLa or HEK293 cell lysate.
• Theoretical MW: 40 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for UFD1L Antibody (5e2)

• ATP1C
• ATP1G1ATPase, Na+/K+ transporting, gamma 1 polypeptide
• FXYD domain containing ion transport regulator 2
• FXYD domain-containing ion transport regulator 2
• HOMG2
• hypomagnesemia 2, renal
• MGC12372
• Na(+)/K(+) ATPase subunit gamma
• Sodium pump gamma chain
• sodium/potassium-transporting ATPase subunit gamma
• Sodium-potassium-ATPase, gamma polypeptide

Background

The protein encoded by the UFD1L gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: UFD1