Uev1a/UBE2V1 Antibody Blocking Peptide

Product Discontinued

Uev1a/UBE2V1 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 15 amino acids near the carboxy terminus of human UEV1A.

  Source: Synthetic

  (Accession #: NP_954595)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: UBE2V1
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-76442.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for Uev1a/UBE2V1 Antibody Blocking Peptide

• CIR1
• CROC1
• CROC1TRAF6-regulated IKK activator 1 beta Uev1A
• CROC-1UBE2V
• UBE2V1
• ubiquitin-conjugating enzyme E2 variant 1
• Uev1a
• UEV-1CIR1
• UEV1DNA-binding protein

Background

Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: UBE2V1