TUSC4 Antibody

Western Blot: TUSC4 Antibody [H00010641-B01P] - Analysis of TUSC4 expression in Raw 264.7.

Immunocytochemistry/Immunofluorescence: TUSC4 Antibody [H00010641-B01P] - Analysis of purified antibody to TUSC4 on HeLa cell. (antibody concentration 10 ug/ml)

Western Blot: TUSC4 Antibody [H00010641-B01P] - TUSC4 MaxPab polyclonal antibody. Western Blot analysis of TUSC4 expression in human liver.

Western Blot: TUSC4 Antibody [H00010641-B01P] - Analysis of TUSC4 expression in transfected 293T cell line by TUSC4 polyclonal antibody. Lane 1: TUSC4 transfected lysate(41.91 KDa). Lane 2: Non-transfected lysate.

• Reactivity: Hu, Mu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated

TUSC4 Antibody Summary

• Immunogen: TUSC4 (AAH21984.1, 1 a.a. - 380 a.a.) full-length human protein. MGSGCRIECIFFSEFHLTLGPKITYQVPEDFISRELFDTVQVYIITKPEPQNKLITVTAMEKKLIGCPVCIEHKKYSRNALLFNLGFVCDAQAKTCALEPIVKKLAGYLTTLELESSFVSMEESKQKLVPIMTILLEELNASGRCTLPIDESNTIHLKVIEQRPDPPVAQEYDVPVFTKDKEDFFNSQWDLTTQQILPYIDGFRHIQKISAEADVELNLVRIAIQNLLYYGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKRASLRDVFQLYCSLSPGTTVRDLIGRHPQQLQHVDERKLIQFGLMKNLIRRLQKYPVRVTREEQSHPARLYTGCHSYDEICCKTGMSYHELDERLENDPNIIICWK
• Specificity: TUSC4 - tumor suppressor candidate 4,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: NPRL2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TUSC4 Antibody

• G21 protein
• Gene 21 protein
• homologous to yeast nitrogen permease (candidate tumor suppressor)
• nitrogen permease regulator 2-like protein
• nitrogen permease regulator-like 2 (S. cerevisiae)
• NPR2
• NPR2L2810446G01Rik
• NPRL2
• Tumor suppressor candidate 4NPR2-like protein
• TUSC4

Background

Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NPRL2
• Entrez:
  • 10641(Human)
• Uniprot:
  • AAH21984.1(Human)