TUSC4 Products

Description

Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs

Bioinformatics

Entrez	10641 Human 56032 Mouse
Uniprot	AAH21984 Human AAH21984.1 Human NM_006545 Human NP_006536 Human NP_006536.3 Human
Product By Gene ID	10641
Alternate Names	G21 protein Gene 21 protein homologous to yeast nitrogen permease (candidate tumor suppressor) nitrogen permease regulator 2-like protein nitrogen permease regulator-like 2 (S. cerevisiae) NPR2 NPR2L2810446G01Rik NPRL2 Tumor suppressor candidate 4NPR2-like protein TUSC4

Research Areas for TUSC4

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Cell Cycle and Replication