TSLPR/CRLF2 Antibody

Immunohistochemistry-Paraffin: TSLP R/CRLF2 Antibody [NBP2-27288] - Formalin-fixed, paraffin-embedded normal human lung tissue stained with TSLP receptor antibody (5 ug/ml), peroxidase-conjugate and DAB chromogen.

Product Discontinued

TSLPR/CRLF2 Antibody Summary

• Immunogen: Amino acids 145-178 of human TSLP receptor protein were used as the immunogen for the antibody.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CRLF2
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:400

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 0.1 ml crude antibody whole antisera with 50% Glycerol
• Preservative: 0.025% Sodium Azide
• Purity: Unpurified

Alternate Names for TSLPR/CRLF2 Antibody

• CRL2
• CRL2cytokine receptor CRL2 precusor
• CRLF2
• CRLF2Y
• CRLM-2
• Cytokine receptor-like 2
• cytokine receptor-like factor 2
• ILXR
• IL-XR
• P2RY8/CRLF2 fusion
• PCOR1
• Thymic stromal lymphopoietin protein receptor
• thymic stromal lymphopoietin receptor
• thymic stromal-derived lymphopoietin receptor
• TSLP R
• TSLP receptor
• TSLPR

Background

TSLP receptor (TSLPR, TSLP-R) is a member of the hematopoietin receptor family which acts as a receptor for the cytokine thymic stromal lymphopoietin (TSLP) that promotes CD4(+) T cell homeostasis and contributes to allergic and inflammatory responses. TSLP receptor is a heterodimeric complex, consisting of the IL-7R-alpha chain and a common gamma-like receptor chain. The protein contains two fibronectin type III-like domains, four conserved cysteine residues, and a WSXWS box-like motif at it's N-terminal, while the C-terminal intracellular region contains box 1 and box 2-like motifs. The protein is usually expressed in liver, kidney, heart, and skeletal muscle. The gene for human TSLP receptor is localized to the pseudoautosomal region, Xp22.3 and Yp11.3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CRLF2