Tomosyn Antibody [PE]

Product Discontinued

Tomosyn Antibody [PE] Summary

• Immunogen: syntaxin binding protein 5(tomosyn). (Uniprot# Q5T5C0)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: STXBP5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunofluorescence
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Tomosyn Antibody [PE]

• FLJ30922
• Lethal(2) giant larvae protein homolog 3
• LGL3
• LLGL3Nbla04300
• MGC141942
• MGC141968
• putative protein product of Nbla04300
• syntaxin binding protein 5 (tomosyn)
• syntaxin-binding protein 5
• tomosyn
• tomosyn-1

Background

Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Competes with STXBP1 for STX1 binding.; SUBUNIT: Part of a complex that contains STXBP5, STX4A and SNAP23. Interacts with STX1A and STX4A via its v-SNARE homology domain. Part of a complex that contains STX1, STXBP5, SNAP25 and SYT1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: STXBP5