TNFAIP2 Antibody

Immunohistochemistry-Paraffin: TNFAIP2 Antibody [NBP2-27085] - Analysis of human kidney probed with TNFAIP2 antibody at 5 ug/ml.

Product Discontinued

TNFAIP2 Antibody Summary

• Immunogen: A portion of amino acids 320-370 from human TNFAIP2 was used as the immunogen for this antibody.
• Predicted Species: Orangutan (94%), Chimpanzee (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TNFAIP2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5ug/ml

Reactivity Notes

The amino acid sequence used as immunogen for this antibody is 94% in White-cheeked Gibbon, 81% in New World Monkey, Rhesus Macaque.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 ml PBS and 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein A purified

Alternate Names for TNFAIP2 Antibody

• B94
• EXOC3L3
• exocyst complex component 3-like 3
• Primary response gene B94 protein
• TNF alpha-induced protein 2
• tumor necrosis factor alpha-induced protein 2
• tumor necrosis factor, alpha-induced protein 2

Background

TNFAIP2, or TNF alpha inducible protein 2, is a 75kDa protein which has been identified to be highly expressed in cancer cells, particularly nasopharyngeal carcinomas. In these cells TNFAIP2 also appears to promote nasopharyngeal migration (1). TNFAIP2 distinctly may serve as a biomarker for dendritic or histiocytic sarcomas. Abberant expression of TNFAIP2 in these cells in classical Hodgkins Lymphoma or primary mediastinal (thymic) B cell lymphoma also may delineate these cells from other large cell lymphomas (2). Other earlier studies have shown TNFAIP2 to be highly expressed by Northern in lymphoid and myeloid tissues and may be considered to promote myeloid development (3, 4). It is interesting to compare TNFAIP2 in further analysis with, which is another TNFa inducible protein albeit more well-characterized as an apoptotic inhibitor which activates NF-kB.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TNFAIP2
• Uniprot:
  • Q03169(Human)