TMEM34 Antibody

Images

 
Western Blot: TMEM34 Antibody [NBP1-77144] - Analysis of TMEM184C in mouse heart tissue lysate with TMEM184C antibody at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: TMEM34 Antibody [NBP1-77144] - Immunofluorescence of TMEM184C in mouse heart tissue with TMEM184B antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: TMEM34 Antibody [NBP1-77144] - Mouse heart tissue with TMEM184C antibody at 5 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

TMEM34 Antibody Summary

Immunogen
Antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TMEM184C. The immunogen is located within amino acids 340 - 390 of TMEM184C.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TMEM184C
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
TMEM34 Peptide (NBP1-77144PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TMEM34 Antibody

  • TMEM34
  • transmembrane protein 184C
  • Transmembrane protein 34FLJ10846

Background

Anaplastic thyroid cancer is one of the most lethal forms of cancer, but the precise carcinogenic mechanism has not been identified. TMEM184C, also known as TMEM34, was identified in a cDNA microarray analysis as being down-regulated in anaplastic thyroid cancers compared to normal thyroid tissues. TMEM184C protein expression was also lower in cell lines derived from these types of cancers compared to that of normal thyroid tissues or cell lines based on other types of thyroid cancers. Furthermore, transfection of TMEM34 into KTA2 cells led to the inhibition of cell growth, suggesting that TMEM184C might act as a tumor suppressor in anaplastic thyroid cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TMEM34 Antibody (NBP1-77144) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for TMEM34 Antibody (NBP1-77144)

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Bioinformatics

Gene Symbol TMEM184C
Uniprot