TMEFF1/Tomoregulin-1 Antibody (249511) [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: WB
• Clone: 249511
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

TMEFF1/Tomoregulin-1 Antibody (249511) [Alexa Fluor® 750] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human TMEFF1/Tomoregulin‑1
  Ser40-Thr328
  Accession # Q8IYR6
• Specificity: Detects human TMEFF1/Tomoregulin‑1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse TMEFF1 or recombinant human TMEFF2 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TMEFF1/Tomoregulin-1 Antibody (249511) [Alexa Fluor® 750]

• C9orf2
• H7365member 1
• TMEFF1
• Tomoregulin1
• Tomoregulin-1
• TR-1
• Transmembrane protein with EGF-like and one follistatin-like domain
• transmembrane protein with EGF-like and two follistatin-like domains 1

Background

TMEFF1 (Transmembrane protein with EGF-like and two Follistatin-like domains 1), also known as tomoregulin 1 is a type I transmembrane glycoprotein that contains two follistatin modules and an EGF domain in its extracellular domain, a transmembrane domain and a short cytoplasmic tail. The extracellular domain can be released as a soluble protein. TMEFF1 selectively regulates nodal but not activin signaling through direct binding to the nodal co-receptor, Cripto.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.