Tight Junction Protein 2 Antibody

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Western Blot: Tight Junction Protein 2 Antibody [NBP2-20641] - Tight junction protein 2 Antibody [NBP2-20641] - Sample (30 ug of whole cell lysate) A: U87-MG 5% SDS PAGE gel, diluted at 1:500.

Product Details

Summary
Reactivity Hu, CaSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Tight Junction Protein 2 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human TJP2. The exact sequence is proprietary.
Localization
Cell junction; adherens junction; Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity); tight junction (By similarity); Nucleus (By similarity)
Marker
Intercellular Junctions Marker
Predicted Species
Canine (91%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TJP2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
134 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse (87%), Rat (86%), Pig (88%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Tight Junction Protein 2 Antibody

  • C9DUPq21.11
  • DFNA51
  • DUP9q21.11
  • MGC26306
  • tight junction protein 2 (zona occludens 2)
  • Tight junction protein 2
  • TJP2
  • X104
  • X104tight junction protein ZO-2
  • ZO2
  • ZO-2
  • ZO2Friedreich ataxia region gene X104 (tight junction protein ZO-2)
  • Zona occludens protein 2
  • Zonula occludens protein 2

Background

Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Blogs on Tight Junction Protein 2.

Zonula Occludens (ZO) the Junction Scaffolding Proteins
The Zonula Occludens (ZO) proteins 1,2 and 3, also known as tight junction proteins, are peripheral proteins localizing at junctional sites(1). ZO proteins are known to be scaffolding proteins recruiting various types of proteins to the cytoplasmic...  Read full blog post.

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Bioinformatics

Gene Symbol TJP2
Uniprot