Tight Junction Protein 2 Products

Antibodies
Tight Junction Protein 2 Anti ...
Tight Junction Protein 2 Antibody
NBP1-86850
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Tight Junction Protein 2 Anti ...
Tight Junction Protein 2 Antibody
NBP1-57902
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-Fr
Host: Guinea Pig Polyclonal
Tight Junction Protein 2 Anti ...
Tight Junction Protein 2 Antibody
NBP1-49667
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-Fr
Host: Guinea Pig Polyclonal
Lysates
Tight Junction Protein 2 Over ...
Tight Junction Protein 2 Overexpre...
NBL1-16938
Applications: WB
Tight Junction Protein 2 Over ...
Tight Junction Protein 2 Overexpre...
H00009414-T01
Applications: WB
Proteins
Tight Junction Protein 2 Part ...
Tight Junction Protein 2 Partial R...
H00009414-Q01
Species: Hu
Applications: WB, ELISA, PA
Tight Junction Protein 2 Reco ...
Tight Junction Protein 2 Recombina...
NBP1-86850PEP
Species: Hu
Applications: AC
RNAi
Tight Junction Protein 2 RNAi ...
Tight Junction Protein 2 RNAi
H00009414-R04
Species: Hu
Tight Junction Protein 2 RNAi ...
Tight Junction Protein 2 RNAi
H00009414-R03
Species: Hu

Description

TJP2 - tight junction protein 2 (zona occludens 2). embers of this family are involved in epithelial and endothelial intercellular junctions. They each contain at least one PSD95/Dlg/ZO-1 (PDZ) domain, a Src homology 3 (SH3) domain, and an enzymatically inactive guanylate kinase domain. PDZ domains are 90-amino acid protein-protein binding domains that recognize at least a 3-residue peptide motif in the COOH termini of their binding partners. PDZ domain-containing proteins, like ZO-2, typically act as scaffolding proteins that organize membrane receptors and cytosolic proteins into multimeric signaling complexes often at the sites of cell-cell contact. The effectiveness and stability of the epithelial barrier depends on a complex of proteins composing different intercellular junctions, which include tight junctions, adherens junctions, and desmosomes. ZO-2 can interact with zona occludens 1 (ZO-1). Furthermore, the PDZ2 domain of ZO-2 was shown to interact with connexin-43, the predominant connexin in epithelial and most other tissues which is involved in cell growth control and embryonic development.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 9414
Alternate Names
  • ZO2
  • TJP2
  • X104
  • DFNA51
  • DUP9q21.11
  • C9DUPq21.11
  • Zona occludens protein 2
  • ZO-2
  • Tight junction protein 2
  • Zonula occludens protein 2
  • X104tight junction protein ZO-2
  • ZO2Friedreich ataxia region gene X104 (tight junction protein ZO-2)
  • MGC26306
  • tight junction protein 2 (zona occludens 2)

PTMs for Tight Junction Protein 2

Learn more about PTMs related to Tight Junction Protein 2.

Phosphorylation
Dephosphorylation
Methylation
Demethylation
Cleavage

Bioinformatics Tool for Tight Junction Protein 2

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Related Tight Junction Protein 2 Blog Posts

Check out the latest blog posts on Tight Junction Protein 2.
Zonula Occludens (ZO) the Junction Scaffolding Proteins
The Zonula Occludens (ZO) proteins 1,2 and 3, also known as tight junction proteins, are peripheral proteins localizing at junctional sites(1). ZO proteins are known to be scaffolding proteins recruiting various types of proteins to the cytoplasmic...    Read more.
Read more Tight Junction Protein 2 related blogs.