Recombinant Human TIFA His Protein

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Recombinant Human TIFA Protein [NBP1-99103]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Human TIFA His Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-184 of Human TIFA

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMTSFED ADTEETVTCL QMTVYHPGQL QCGIFQSISF NREKLPSSEV VKFGRNSNIC HYTFQDKQVS RVQFSLQLFK KFNSSVLSFE IKNMSKKTNL IVDSRELGYL NKMDLPYRCM VRFGEYQFLM EKEDGESLEF FETQFILSPR SLLQENNWPP HRPIPEYGTY SLCSSQSSSP TEMDENES

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
TIFA
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Dilutions
  • SDS-Page
Theoretical MW
24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using NBP1-99103.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 1 mM DTT
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human TIFA His Protein

  • Putative MAPK-activating protein PM14
  • Putative NF-kappa-B-activating protein 20
  • T2BPMGC20791
  • T6BP
  • TIFAA
  • TRAF2 binding protein
  • TRAF2-binding protein
  • TRAF6 binding protein
  • TRAF-interacting protein with a forkhead-associated domain
  • TRAF-interacting protein with FHA domain-containing protein A
  • TRAF-interacting protein with forkhead-associated domain

Background

TIFA, also known as TRAF-interacting protein with FHA domain-containing protein A, is an adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. This protein induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism. Recombinant human TIFA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for TIFA Recombinant Protein (NBP1-99103)(1)

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Bioinformatics

Gene Symbol TIFA