TIFA Products

Description

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in thedownstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6,which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism

Bioinformatics

Entrez	92610 Human
Uniprot	NM_052864 Human NP_443096.1 Human Q96CG3 Human
Product By Gene ID	92610
Alternate Names	Putative MAPK-activating protein PM14 Putative NF-kappa-B-activating protein 20 T2BPMGC20791 T6BP TIFAA TRAF2 binding protein TRAF2-binding protein TRAF6 binding protein TRAF-interacting protein with a forkhead-associated domain TRAF-interacting protein with FHA domain-containing protein A TRAF-interacting protein with forkhead-associated domain