TIAM1 Antibody

Product Discontinued

TIAM1 Antibody Summary

• Immunogen: Human Tiam 1 (N-terminal domain) is a rabbit serum directed against a GST fusion protein with the N-terminal amino acids 80-183 of Tiam 1.
• Specificity: Human Tiam1 (N-terminal domain) recognizes the N-terminal amino acids 80-183 of Tiam 1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TIAM1
• Purity: Whole Antiserum

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:500
  • Immunohistochemistry
  • Immunohistochemistry-Frozen 1:10 - 1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1:100-1:2000
• Application Notes: .

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.2
• Preservative: 0.09% Sodium Azide
• Purity: Whole Antiserum

Alternate Names for TIAM1 Antibody

• FLJ36302
• human T-lymphoma invasion and metastasis inducing TIAM1 protein, 10TIAM-1
• T-cell lymphoma invasion and metastasis 1
• TIAM1
• T-lymphoma invasion and metastasis-inducing protein 1

Background

TIAM1 modulates the activity of RHO like proteins and connects extracellular signals to cytoskeletal activities. It acts as a GDP dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO like GTPases and activates them. It activates RAC1, CDC42, and to a lesser extent RHOA.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TIAM1