Thyroglobulin Antibody (904802) [Unconjugated]

Images

 
Western blot shows lysates of human thyroid tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Thyroglobulin Monoclonal Antibody (Catalog # MAB8306) followed by HRP-conjugated Anti-Mouse IgG Secondary ...read more
Thyroglobulin was detected in immersion fixed paraffin-embedded sections of human thyroid cancer tissue using Mouse Anti-Human Thyroglobulin Monoclonal Antibody (Catalog # MAB8306) at 15 µg/mL overnight at 4 °C. ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
904802
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Formulations
Catalog# & Formulation Size Price

Thyroglobulin Antibody (904802) [Unconjugated] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human Thyroglobulin
Met1-Lys2768
Accession # P01266
Specificity
Detects human Thyroglobulin in direct ELISAs.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TG
Purity
Protein A or G purified from hybridoma culture supernatant
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
  • Immunohistochemistry 8-25 ug/mL
Reviewed Applications
Read 1 Review rated 4
using
MAB8306 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Thyroglobulin Antibody (904802) [Unconjugated]

  • AITD3
  • AITD3TGN
  • cog
  • TDH3
  • Tg
  • TGN
  • Thyroglobulin

Background

Human Thyroglobulin (Tg) gene is localized at position 8q242-8q243. The gene covers a genome area of at least 300 000 bp and contains at least 37 exons. Thyroglobulin (Tg) is a dimeric 660 kDa glycoprotein produced by follicular cells (thyrocytes) in thyroid gland and stored in the follicular colloid of the gland. Tg is heterogenic due to post-translational modifications, such as iodination, glycosylation, sulfatation, phosphorylation and it is highly sensitivity to proteolysis.  Acting as a substrate, Tg is used for the synthesis of thyroid hormones thyroxine (T4) and triiodothyronine (T3).  Tg level can serve as a tumor marker of papillary and follicular thyroid cancer and elevated levels of anti-Tg antibodies in blood can be indicative of Graves disease. 

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-85466
Species: Hu, Mu, Fe
Applications: WB, IHC, IHC-P
AF7895
Species: Hu
Applications: WB, IHC
NBP2-34260
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-80670
Species: Hu
Applications: WB, IHC, IHC-P
AF7197
Species: Hu, Mu
Applications: WB, IHC, ICC
NBP2-92630
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NB600-41532
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P
NB600-609
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
NBP2-37477
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NBP2-44501
Species: Hu, Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, IF
NBP2-19860
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NB120-14817
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, S-ELISA
NBP2-20383
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P

Publications for Thyroglobulin Antibody (MAB8306) (0)

There are no publications for Thyroglobulin Antibody (MAB8306).
By submitting your publication information earn gift cards and discounts for future purchases.

Review for Thyroglobulin Antibody (MAB8306) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: horse.

Reviews using MAB8306:
Filter by Applications
IHC-P
(1)
All Applications
Filter by Species
horse
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Paraffin Thyroglobulin MAB8306
Enlarge
4
reviewed by:
Christof Bertram
IHC-P horse 01/26/2017
View

Summary

ApplicationImmunohistochemistry-Paraffin
Sample Testedthyroid gland and thyroid follicular tumor
Specieshorse
LotCISD011611A

Comments

CommentsApplication: Immunohistochemistry

Species: Horse
Dilution: 1:100
Pretreatment for antigen retrieval: microwave heating with citrate buffer for 12 minutes at 600 watts

Results: positive staining of follicular epithelium

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Thyroglobulin Antibody (MAB8306) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Additional Thyroglobulin Products

Bioinformatics Tool for Thyroglobulin Antibody (MAB8306)

Discover related pathways, diseases and genes to Thyroglobulin Antibody (MAB8306). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Thyroglobulin Antibody (MAB8306)

Discover more about diseases related to Thyroglobulin Antibody (MAB8306).
 

Pathways for Thyroglobulin Antibody (MAB8306)

View related products by pathway.

PTMs for Thyroglobulin Antibody (MAB8306)

Learn more about PTMs related to Thyroglobulin Antibody (MAB8306).

Blogs on Thyroglobulin.

TTF1 / NKX2.1 - An essential regulator of lung development with implications in cancer diagnostics
Thyroid transcription factor 1 (TTF-1), also known as NKX2.1, is a conserved master regulatory transcription factor involved in the development of the lung, brain, and thyroid (1). In the lung TTF-1 positively regulates the expression of several lu...  Read full blog post.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Recent Reviews

4
5
0
4
1
3
0
2
0
1
0

Christof Bertram
01/26/2017
Application: IHC-P
Species: horse

Bioinformatics

Gene Symbol TG
Uniprot