Thyroglobulin Products

Antibodies
Thyroglobulin Antibody (90480 ...
Thyroglobulin Antibody (904802) [U...
MAB8306
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Thyroglobulin Antibody (CL016 ...
Thyroglobulin Antibody (CL0164)
NBP2-14784
Species: Hu
Applications: WB, IHC, IHC-P
Host: Mouse Monoclonal
ELISA Kits
Thyroglobulin ELISA Kit [HRP] ...
Thyroglobulin ELISA Kit [HRP]
KA0951
Species: Hu
Thyroglobulin ELISA Kit [HRP] ...
Thyroglobulin ELISA Kit [HRP]
KA1121
Thyroglobulin ELISA Kit [HRP] ...
Thyroglobulin ELISA Kit [HRP]
KA1119
Proteins
Thyroglobulin Partial Recombi ...
Thyroglobulin Partial Recombinant ...
H00007038-Q02
Species: Hu
Applications: WB, ELISA, PA
Thyroglobulin Partial Recombi ...
Thyroglobulin Partial Recombinant ...
H00007038-Q01
Species: Hu
Applications: WB, ELISA, PA
Thyroglobulin Recombinant Pro ...
Thyroglobulin Recombinant Protein ...
NBP1-90200PEP
Species: Hu
Applications: AC
RNAi
Thyroglobulin RNAi
Thyroglobulin RNAi
H00007038-R01
Species: Hu

Description

Thyroglobulin is synthesized by the follicular epithelial cells of the thyroid. Thyroglobulin is the glycoprotein precursor to the thyroid hormones. Its synthesis and metabolism have seemingly wasteful features. It has a molecular weight of 660,000, with 2 identical subunits of MW 300,000 and 10% sugars; yet its complete hydrolysis yields only 2 to 4 molecules of the iodothyroxines T4 and T3. Baas et al. (1986) showed that the TG gene encodes an 8.7-kb mRNA, covers at least 300 kb of genomic DNA and contains at least 37 exons separated by introns as large as 64 kb. A striking structural difference between the 5-prime and 3-prime parts of the gene suggested that it is composed of 2 evolutionarily different regions. The first 30 kb of DNA encodes 3 kb of the mRNA yielding an exon:intron ratio of 1:10, whereas the remaining 270 kb encodes 5.7 kb of the mRNA with a ratio of 1.47.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 7038
Alternate Names
  • TDH3
  • Tg
  • AITD3TGN
  • thyroglobulin

Research Areas for Thyroglobulin

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Biology

Bioinformatics Tool for Thyroglobulin

Discover related pathways, diseases and genes to Thyroglobulin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Thyroglobulin Blog Posts

Check out the latest blog posts on Thyroglobulin.
TTF1 / NKX2.1 - An essential regulator of lung development with implications in cancer diagnostics
Thyroid transcription factor 1 (TTF-1), also known as NKX2.1, is a conserved master regulatory transcription factor involved in the development of the lung, brain, and thyroid (1). In the lung TTF-1 positively regulates the expression of several lu...    Read more.
Read more Thyroglobulin related blogs.