THAP1 Recombinant Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

THAP1 Recombinant Protein Summary

Description
A recombinant protein with a His-tag corresponding to amino acids 1 to 213 of Human THAP1

Source: E. coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMVQSCS AYGCKNRYDK DKPVSFHKFP LTRPSLCKEW EAAVRRKNFK PTKYSSICSE HFTPDCFKRE CNNKLLKENA VPTIFLCTEP HDKKEDLLEP QEQLPPPPLP PPVSQVDAAI GLLMPPLQTP VNLSVFCDHN YTVEDTMHQR KRIHQLEQQV EKLRKKLKTA QQRCRRQERQ LEKLKEVVHF QKEKDDVSER GYVILPNDYF EIVEVPA
Preparation
Method
E.coli
Gene
THAP1
Purity
>85%, by SDS-PAGE

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Conjugate
Unconjugated
Buffer
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M Urea, 10% glycerol, 1mM DTT, 0.2M NaCl
Concentration
1 mg/ml
Purity
>85%, by SDS-PAGE

Applications/Dilutions

Application Notes
The purity of this protein is > 85% by SDS-PAGE. Molecular weight is 27.5 kDa (237aa)

Reactivity Notes

Human

Alternate Names for THAP1 Recombinant Protein

  • 4833431A01Rik
  • dystonia 6, torsion (autosomal dominant)
  • DYT6
  • FLJ10477
  • MGC33014
  • nuclear proapoptotic factor
  • THAP domain containing, apoptosis associated protein 1
  • THAP domain protein 1
  • THAP domain-containing protein 1

Background

THAP domain-containing protein 1, also known as THAP1, is a 213 amino acid protein that localizes to the nucleoplasm and contains one THAPtype zinc finger, a conserved DNA-binding domain. It is a DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. THAP1 may also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis. Recombinant human THAP1protein, fused to His-tag at N-terminus, was expressed in E.coli.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol THAP1

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