WB: Approx 55kDa band observed in nuclear lysates of cell lines NIH3T3, HeLa and Jurkat (calculated MW of 52.9kDa according to NP_009093.1). ChIP:This antibody was confirmed in ChIP on SK-MEL-5 cells. This antibody was obtained from a previous batch (different goat).. IHC: In paraffin embedded Human Kidney cancer shows strong nuclear staining of invading cells. Data obtained from previous batch (different goat).
Read 1 Review rated 3 using NB100-1030 in the following applications:
Predicted cross-reactivity based on sequence identity: Mouse, Rat, Canine, Porcine, Bovine.
Alternate Names for TFEB Antibody
Class E basic helix-loop-helix protein 35
T-cell transcription factor EB
transcription factor EB
Transcription factors of the basic helix-loop-helix zipper (bHLH-ZIP) family contain a basic domain, used for DNA binding, and HLH and ZIP domains, both used for oligomerization. TFEB was isolated from a human B-cell cDNA library using a binding sequence from the adenovirus major late promoter. This transcription factor probably binds to the USF/MLTF site and probably recognizes E-box sequences in the heavy-chain immunoglobulin enhancer.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.