TFEB Products

Antibodies
TFEB Antibody
TFEB Antibody
NB100-1030
Species: Hu
Applications: WB, ChIP, IHC, IHC-Fr, IHC-P, PEP-ELISA
Host: Goat Polyclonal
TFEB Antibody (3E1-G6)
TFEB Antibody (3E1-G6)
H00007942-M01
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
TFEB Antibody
TFEB Antibody
NBP2-12758
Species: Hu, Bovine, Equine, Goat, Primate, Porcine, Rhesus Macaque
Applications: WB, IP
Host: Rabbit Polyclonal
Lysates
TFEB Overexpression Lysate (N ...
TFEB Overexpression Lysate (Native)
NBL1-16838
Applications: WB
Proteins
TFEB Recombinant Protein
TFEB Recombinant Protein
H00007942-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
TFEB RNAi
TFEB RNAi
H00007942-R01
Species: Hu

Description

Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 7942
Alternate Names
  • T-cell transcription factor EB
  • ALPHATFEB
  • BHLHE35
  • Class E basic helix-loop-helix protein 35
  • TCFEBbHLHe35
  • transcription factor EB

Bioinformatics Tool for TFEB

Discover related pathways, diseases and genes to TFEB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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