Tenascin X Antibody (T2H5)

Images

 
Immunohistochemistry: Tenascin X Antibody (T2H5) [NB500-513] - Fig. 1. Immunohistochemistry staining of tonsil (paraffin-embedded sections) with anti-human Tenascin X Antibody (T2H5).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P, IP
Clone
T2H5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Tenascin X Antibody (T2H5) Summary

Immunogen
Protein preparation from a homogenate of a human mammary tumour specimen.
Specificity
The antibody T2H5 recognizes tenascin, a large hexameric extracellular matrix glycoprotein.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TNXB
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:200
  • Immunoprecipitation 1:50
Application Notes
Immunohistochemical detection of tenascin is valuable for studies of tissue differentiation and tumour growth. The antibody T2H5 is excellent for staining of paraffin-embedded tissue sections.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS (approx. pH 8.0)
Preservative
15mM Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A purified

Alternate Names for Tenascin X Antibody (T2H5)

  • Hexabrachion-like protein
  • HXBL
  • Tenascin X
  • tenascin XB
  • tenascin XB2
  • tenascin-X
  • TNX
  • TNXB
  • TNXB1growth-inhibiting protein 45
  • TNXB2tenascin XB1
  • TNXBS
  • TNXBSTNXTENX
  • XB
  • XBS
  • XB-S
  • XBTN-X

Background

TNXB is a high molecular weight, multifunctional, hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neovasculature and stroma of undifferentiated tumors. It has been described under a variety of names: cytotactin, hexabrachion protein, J1, myotendinous antigen (MI) and glioma mesenchymal extracellular matrix (GMEM). The tenascin molecule is a disulfide-linked hexamer. The expression of tenascin is associated with development and growth, both normal and pathological, whereas the distribution in normal adult tissue is restricted.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TNXB
Entrez