TEM5/GPR124 Antibody (499708) [Alexa Fluor® 700]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 499708
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 700

TEM5/GPR124 Antibody (499708) [Alexa Fluor® 700] Summary

• Additional Information: Human TEM5/GPR124 MAb (Clone 499708)
• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human TEM5/GPR124
  Met1-Leu699
  Accession # Q96PE1
• Specificity: Detects human TEM5/GPR124 in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: ADGRA2
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TEM5/GPR124 Antibody (499708) [Alexa Fluor® 700]

• DKFZp434C211
• DKFZp434J0911
• G protein-coupled receptor 124
• GPR124
• G-protein coupled receptor 124
• KIAA1531
• KIAA1531FLJ14390
• TEM5
• TEM5Tumor endothelial marker 5

Background

G protein-coupled receptor 124 (GPR124, also known as TEM5), is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. GPR124 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. This receptor mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans. GPR124 has also been shown to interact with DLG1 through its PDZ-binding motif.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADGRA2