TCIRG1 Antibody

ELISA: TCIRG1 Antibody [43480002]

Product Discontinued

TCIRG1 Antibody Summary

• Immunogen: This antibody is specific for the N Terminus Region of the target protein.
• Specificity: This product is specific for Human TCIRG1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TCIRG1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:5000-1:20000
• Application Notes: This antibody is useful in ELISA and Western Blot.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for TCIRG1 Antibody

• a3
• Atp6i
• ATP6N1C
• ATP6N1Cspecific 116-kDa vacuolar proton pump subunit
• ATP6V0A3T-cell immune response cDNA 7
• OC-116 kDa
• OC116
• OC-116
• OC-116kDa
• OC116Vph1
• OPTB1
• Osteoclastic proton pump 116 kDa subunit
• Stv1
• T-cell immune regulator 1
• T-cell immune response cDNA7 protein
• T-cell, immune regulator 1
• T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a
• T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
• T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein aisoform 3
• T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
• TCIRG1
• TIRC7
• TIRC7ATPase, H+ transporting, 116kD
• Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3
• vacuolar proton translocating ATPase 116 kDa subunit A
• V-ATPase 116 kDa isoform a3
• V-ATPase 116-kDa
• Vph1
• V-type proton ATPase 116 kDa subunit a isoform 3
• V-type proton ATPase 116 kDa subunit a

Background

Through alternate splicing, this gene encodes two proteins with similarity to subunits of the vacuolar ATPase (V-ATPase) but the encoded proteins seem to have different functions. V-ATPase is a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Mutations in this gene are associated with infantile malignant osteopetrosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TCIRG1 Antibody (43480002)(2)

Publications using 43480002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Bioinformatics

• Gene Symbol: TCIRG1
• Entrez:
  • 10312(Human)
• Uniprot:
  • Q13488(Human)