TAP1 Antibody (TAP1.28)

Western Blot: TAP1 Antibody (TAP1.28) [NBP1-54435] - Western Blot analysis of TAP1 expression using NBP1-54435 in LCL721 cells

Flow Cytometry: TAP1 Antibody (TAP1.28) [NBP1-54435] - Fow cytometric analysis of TAP1 expression on LCL721 cells. Open histogram indicated the reaction of isotypic control to the cells. Shaded histogram indicated the reaction of NBP1-54435 to the cells.

Immunoprecipitation: TAP1 Antibody (TAP1.28) [NBP1-54435] - Immunoprecipitation of TAP1 from LCL721 celss with (1) NBP1-54435 or (2) mouse IgG. After immunoprecipitated with the antibody, immunocomplex was resolved on SDS-PAGE and immunoblotted with NBP1-54435.

Product Discontinued

TAP1 Antibody (TAP1.28) Summary

• Immunogen: The immunogen for this antibody is TAP1. The exact immunogenic sequence is proprietary.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: TAP1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 ug/ml (final concentration)
  • Immunoprecipitation 10 ug/200uL of cell extract from 1 million cells
  • Western Blot 10 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 50% Glycerol
• Preservative: No Preservative
• Concentration: 1.0 mg/ml
• Purity: Protein A purified

Alternate Names for TAP1 Antibody (TAP1.28)

• ABC Transporter, MHC 1
• ABC17
• ABCB2
• ABCB2FLJ41500
• antigen peptide transporter 1
• APT1
• ATP-binding cassette sub-family B member 2
• ATP-binding cassette, sub-family B (MDR/TAP), member 2
• D6S114E
• Ham1
• Peptide supply factor 1
• Peptide transporter involved in antigen processing 1
• Peptide transporter PSF1
• Peptide Transporter TAP1
• PSF1
• PSF-1
• PSF1ABC17
• Really interesting new gene 4 protein
• RING4
• RING4FLJ26666
• TAP1
• TAP1*0102N
• TAP1N
• transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
• transporter associated with antigen processing
• transporter, ATP-binding cassette, major histocompatibility complex, 1
• Y3

Background

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TAP1