Syntaxin 1A Antibody - BSA Free

Immunohistochemistry-Paraffin: Syntaxin 1A Antibody [NBP3-14491] - Immunohistochemistry of formalin-fixed, paraffin-embedded human brain, cortex, after heat-induced antigen retrieval.

• Reactivity: Hu, Mu, Rt, Po, Av, Bt, Bv, Ca, Eq, Ha, Pm, Ma-Op, Pm-Or, Pm, Xp
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Syntaxin 1A Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 15 amino acid peptide from N-Terminus of human Syntaxin 1A.
• Epitope: N-Terminus
• Specificity: Human Syntaxin 1A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Mouse (100%), Rat (100%), Porcine (100%), Bovine (93%), Orangutan (100%), Opossum (93%), Avian (93%), Hamster (100%), Canine (93%), Bat (93%), Equine (93%), Primate (100%), Monkey (100%), Xenopus (100%). Backed by our 100% Guarantee.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: STX1A
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: .

Reactivity Notes

Expected reactivity based on percent sequence identity: Drosophila, Insect (80%)

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Syntaxin 1A Antibody - BSA Free

• Brain Syntaxin
• HPC-1
• Neuron-specific antigen HPC-1
• p35-1
• STX1A
• STX1P35-1
• SYN1A
• syntaxin 1A (brain)
• Syntaxin 1A
• syntaxin-1A

Background

Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor (MIM 600565) which produces explosive exocytosis (Zhang et al., 1995 [PubMed 7622072]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: STX1A