STI1 Antibody [DyLight 650]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: DyLight 650

STI1 Antibody [DyLight 650] Summary

• Immunogen: E. coli-derived recombinant human STI1
  Met1-Arg543
  Accession # P31948
• Specificity: Detects human, mouse, rat STI1 in Western blots and detects recombinant human STI1 in direct ELISAs.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: STIP1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for STI1 Antibody [DyLight 650]

• HOP
• HOPSTI1L
• Hsc70/Hsp90-organizing protein
• Hsp70/Hsp90-organizing protein
• IEF-SSP-3521
• NY-REN-11 antigen
• NY-REN-11
• Renal carcinoma antigen NY-REN-11
• STI1
• STI1L
• STI1P60
• STIP1
• stress-induced-phosphoprotein 1
• Transformation-sensitive protein IEF SSP 3521

Background

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 (PubMed 16100115)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: STIP1