Stathmin-2/STMN2 Antibody (684433) [Alexa Fluor® 532]

• Reactivity: Hu, Mu
• Applications: WB, IHC
• Clone: 684433
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

Stathmin-2/STMN2 Antibody (684433) [Alexa Fluor® 532] Summary

• Immunogen: E. coli-derived recombinant human Stathmin-2/STMN2
  Tyr26-Gly179
  Accession # Q93045
• Specificity: Detects human Stathmin-2/STMN2 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human Stathmin-1, -3, or -4 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Stathmin-2/STMN2 Antibody (684433) [Alexa Fluor® 532]

• FLJ34868
• FLJ50995
• neuron-specific growth-associated protein
• Protein SCG10
• SCG10
• SCG10neuronal growth-associated protein (silencer element)
• SCGN10
• SCGN10stathmin-2
• Stathmin2
• Stathmin-2
• stathmin-like 2
• STMN2
• superior cervical ganglia, neural specific 10
• Superior cervical ganglion-10 protein

Background

Stathmin-2 (STMN2), also known as superior cervical ganglion 10 protein (SCG10), is a 19 kDa microtubule-destabilizing protein that is preferentially expressed in neurons. It promotes neuronal proliferation and migration as well as neurite outgrowth. Stathmin-2 contains a membrane attachment region
(aa 1‑26), a regulatory domain (aa 39-96), and an overlapping coiled-coil domain (aa 75-179). It is subject to phosphorylation of multiple serines within the regulatory domain. Within aa 26‑179, human Stathmin-2 shares 100% and 99% aa sequence identity with mouse and rat Stathmin-2, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.