STAT2 Antibody (545103) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB, IHC, KO
• Clone: 545103
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

STAT2 Antibody (545103) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human STAT2
  Met1-Phe851
  Accession # P52630
• Specificity: Detects human STAT2 in direct ELISAs. In direct ELISAs, this antibody shows no cross-reactivity with rhSTAT1, 1A, 3, 4, 5A, 5B, 6, or rmSTAT2.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Knockout Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for STAT2 Antibody (545103) [Alexa Fluor® 488]

• interferon alpha induced transcriptional activator
• ISGF-3
• MGC59816
• P113
• signal transducer and activator of transcription 2
• signal transducer and activator of transcription 2, 113kD
• signal transducer and activator of transcription 2, 113kDa
• STAT113
• STAT2

Background

Signal transducer and activator of transcription 2 (STAT2) is a 98 kDa member of the transcription factor STAT family. Human STAT2 is 851 amino acids (aa) in length and contains one SH2 domain (aa 572‑667). Splicing variants produce two isoforms for human STAT2. The short isoform has substitutions corresponding to aa 621‑652 and aa 653‑851 in the long isoform, respectively. Human STAT2 shares 73% and 65% aa sequence identity with rat and mouse STAT2, in that order. STAT2 functions as a signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta ).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.