Independent Antibodies: Western Blot: SRGAP1 Antibody [NB100-60650] - Detection of Human SRGAP1/ARHGAP13 on HeLa whole cell lysate using NB100-60650. SRGAP1/ARHGAP13 was also IPed by NB100-60649.
The immunogen recognized by this antibody maps to a region between residue 979 and 1029 of human SLIT-ROBO Rho GTPase activating protein 1 (Rho GTPase-activating protein 13) using the numbering given in entry NP_065813.1 (GeneID 57522).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SRGAP1
Purity
Immunogen affinity purified
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SRGAP1/ARHGAP13 is a member of the srGAP family of proteins that contain a RhoGAP domain, an SH3 domain, and a Fes/CIP4 homology domain and interact with the intracellular domain of roundabout 1 (Robo1). Robo1 is the receptor for Slit signaling and is involved in neuronal cell migration and axon tract positioning. SRGAP1/ARHGAP13 functions to bind and decrease the level of active Cdc42 and RhoA small GTPases during Slit-Robo signaling.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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