SRGAP1 Antibody - BSA Free

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Independent Antibodies: Immunoprecipitation: SRGAP1 Antibody [NB100-60649] - Detection of Human SRGAP1 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml
Validated by:
 

Independent Antibodies

       

Order Details

SRGAP1 Antibody - BSA Free Summary

Description
Novus Biologicals Rabbit SRGAP1 Antibody - BSA Free (NB100-60649) is a polyclonal antibody validated for use in IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
The immunogen recognized by this antibody maps to a region between residue 825 and 875 of human SLIT-ROBO Rho GTPase activating protein 1 (Rho GTPase-activating protein 13) using the numbering given in entry NP_065813.1 (GeneID 57522).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SRGAP1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 2- 5 ug/mg lysate

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SRGAP1 Antibody - BSA Free

  • ARHGAP13srGAP1
  • FLJ22166
  • KIAA1304SLIT-ROBO Rho GTPase-activating protein 1
  • Rho GTPase-activating protein 13
  • SLIT-ROBO Rho GTPase activating protein 1

Background

SRGAP1/ARHGAP13 is a member of the srGAP family of proteins that contain a RhoGAP domain, an SH3 domain, and a Fes/CIP4 homology domain and interact with the intracellular domain of roundabout 1 (Robo1). Robo1 is the receptor for Slit signaling and is involved in neuronal cell migration and axon tract positioning. SRGAP1/ARHGAP13 functions to bind and decrease the level of active Cdc42 and RhoA small GTPases during Slit-Robo signaling. Alternate names for SRGAP1/ARHGAP13 include Rho GTPase-activating protein 13, and KIAA1304.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SRGAP1
Entrez
Uniprot