SOX6 Antibody (CL5690) [Janelia Fluor® 669]

• Reactivity: Hu
• Applications: ICC/IF, IHC
• Clone: CL5690
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 669

SOX6 Antibody (CL5690) [Janelia Fluor® 669] Summary

• Immunogen: This antibody was generated using a synthetic peptide of P35712, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: SOX6
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SOX6 Antibody (CL5690) [Janelia Fluor® 669]

• HSSOX6
• SOX6
• SOXD
• SRY (sex determining region Y)-box 6
• SRY-box containing gene 6
• transcription factor SOX-6

Background

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 Sox genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SOX6