SOST/Sclerostin Antibody (248121) [mFluor Violet 500 SE]

• Reactivity: Mu
• Applications: WB
• Clone: 248121
• Clonality: Monoclonal
• Host: Rat
• Conjugate: mFluor Violet 500 SE

SOST/Sclerostin Antibody (248121) [mFluor Violet 500 SE] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse SOST
  Gln24-Tyr211
  Accession # AAI37834
• Specificity: Detects mouse SOST in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with recombinant human SOST.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat
• Gene: SOST
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SOST/Sclerostin Antibody (248121) [mFluor Violet 500 SE]

• sclerostin
• SOST
• VBCHsclerosteosis

Background

Sclerostin is the product of the gene SOST. Sclerostin is expressed in osteocytes and loss of the gene results in the condition sclerosteosis, which is a disorder in which bone mass is increased due to an increase in osteoblast activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SOST