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HAF017). A specific band was detected for SOST/Sclerostin at approximately 28 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
1406-ST) was serially diluted and captured by Mouse Anti-Human SOST/Sclerostin Monoclonal Antibody (Catalog # MAB1406) coated on a Clear Polystyrene Microplate (Catalog # DY990). Mouse Anti-Human SOST/Sclerostin Biotinylated Monoclonal Antibody (Catalog # [[catalogNumber:) was incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # [[catalogNumber:DY998)" class="big_lightbox" target="_blank">
HAF017). A specific band was detected for SOST/Sclerostin at approximately 28 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
Sclerostin is the product of the gene SOST. Sclerostin is expressed in osteocytes and loss of the gene results in the condition sclerosteosis, which is a disorder in which bone mass is increased due to an increase in osteoblast activity.