SOST/Sclerostin Antibody (220902) [Alexa Fluor® 700]

• Reactivity: Hu
• Applications: WB, ELISA(Cap), ELISA(Det)
• Clone: 220902
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 700

SOST/Sclerostin Antibody (220902) [Alexa Fluor® 700] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human SOST/Sclerostin
  Gln24-Tyr213
  Accession # Q9BQB4
• Specificity: Detects human SOST/Sclerostin in ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse SOST is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SOST/Sclerostin Antibody (220902) [Alexa Fluor® 700]

• sclerostin
• SOST
• VBCHsclerosteosis

Background

SOST, also known as sclerostin, belongs to the Cerberus/DAN family of secreted glycoproteins. SOST binds BMP-5, -6, and -7 with high affinity and BMP-2 and -4 with low affinity and functions in bone homeostasis as a BMP antagonist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.