Somatostatin R3/SSTR3 Antibody (576017)

PC‑3 human prostate cancer cell line was stained with Mouse Anti-Human Somatostatin R3/SSTR3 Monoclonal Antibody (Catalog # MAB7018, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).

• Reactivity: Hu
• Applications: Flow, CyTOF-ready
• Clone: 576017
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

Somatostatin R3/SSTR3 Antibody (576017) Summary

• Immunogen: NS0 mouse myeloma cell line transfected with human Somatostatin R3/SSTR3
  Accession # P32745
• Specificity: Detects human Somatostatin R3/SSTR3
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: SSTR3
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Somatostatin R3/SSTR3 Antibody (576017)

• Somatostatin R3
• somatostatin receptor 3
• SomatostatinR3
• SS-3-R
• SS3-R
• SSR-28
• SST3
• SSTR3

Background

Somatostatin Receptor 3 (SSTR3) is one of five 7-transmembrane G-protein-coupled receptors for somatostatins 14 and 28. Human SSTR3 shares 80% aa identity with mouse SSTR3 within the extracellular domains. SSTR3 protein has been detected in anterior pituitary, lymphocytes, thyroid, parathyroid, stomach, small intestine, and pancreatic islets. In neurons, it is located within cilia and is implicated in object recognition memory. It is an inhibitory receptor that transduces the antiproliferative and antisecretive effects of somatostatins in the pituitary.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SSTR3
• Uniprot:
  • P32745()