SNW1 Antibody (PCRP-SNW1-1C12) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: Flow
• Clone: PCRP-SNW1-1C12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

SNW1 Antibody (PCRP-SNW1-1C12) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
  
  CoraFluor(TM) 1, amine reactive
  
  CoraFluor(TM) 1, thiol reactive
  
  For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
• Immunogen: Recombinant fragment of human SNW1 protein
• Localization: Nucleus, Cytosol
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: SNW1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted to react with chicken, mouse and rat.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for SNW1 Antibody (PCRP-SNW1-1C12) [CoraFluor™ 1]

• Bx42
• homolog of Drosophila BX42
• MGC119379
• NCoA-62
• Nuclear protein SkiP
• Nuclear receptor coactivator NCoA-62
• nuclear receptor coactivator, 62-kD
• Prp45
• PRPF45
• SKI interacting protein
• Ski-interacting protein
• SKIPSKIIP
• SNW domain containing 1
• SNW domain-containing protein 1

Background

SNW1, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SNW1