SMN2 Antibody

Western Blot: SMN2 Antibody [H00006607-B02P] - Analysis of SMN2 expression in transfected 293T cell line by SMN2 polyclonal antibody. Lane 1: SMN2 transfected lysate(32.34 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

SMN2 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: SMN2 (ABM85660.1, 1 a.a. - 294 a.a.) full-length human protein. MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN
• Specificity: This product is specific for Human SMN2 purified MaxPab mouse polyclonal antibody (B02P) [Gene ID: 6607].
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: SMN2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SMN2 Antibody

• BCD541
• C-BCD541
• Component of gems 1
• FLJ76644
• gemin 1
• gemin-1
• MGC20996
• MGC5208
• SMN
• SMNCSMN1
• SMNT
• survival motor neuron protein
• survival of motor neuron 2, centromeric

Background

Gemin 1 (SMN) is the central component of a large oligomeric complex (SMN complex), including Gemins 2-7, that is necessary and sufficient for the in vivo assembly of Sm proteins onto the small nuclear (sn)RNAs that mediate pre-mRNA splicing. The SMN complex is found in the cytoplasm and nucleus. Within the nucleus, this protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). Spinal muscular atrophy, a motor neuron disorder, results from reduced levels or a mutation in the Gemin 1 protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SMN2
• Uniprot:
  • ABM85660.1(Human)