SMARCA6 Recombinant Enzymes

• Reactivity: Hu
• Applications: NULL

SMARCA6 Recombinant Enzymes Summary

• Description: Human HELLS (aa 1-822) fused to 6xHis and FLAG-tag at the N-terminus. (Uniprot: Q9NRZ9-2)
• Source: Sf 9 (baculovirus)
• Protein/Peptide Type: Recombinant Enzymes
• Gene: HELLS
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • N/A

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl, pH 7.9, 150 mM NaCl, 15% glycerol, 2 mM MgCl2, 0.2 mM EDTA, 1 mM DTT, 10 mM beta-glycerophospate, 0.4 mM PMSF, 1 mM benzamidine and 0.4 mg/ml recombinant human insulin
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for SMARCA6 Recombinant Enzymes

• EC 3.6.1
• EC 3.6.4.-
• helicase, lymphoid-specific
• LSHSWI/SNF2-related, matrix-associated, actin-dependent regulator of chromatin
• Nbla10143
• PASGFLJ10339
• Proliferation-associated SNF2-like protein
• SMARCA6lymphoid-specific helicase
• subfamily A, member 6
• SWI/SNF2-related matrix-associated actin-dependent regulator of chromatinsubfamily A member 6

Background

HELLS, also known as LSH (lymphoid specific helicase), is a member of the SNF2 superfamily of chromatin helicases. HELLS is ubiquitously expressed and is required for the maintenance of normal DNA methylation patterns important to organism development. HELLS function has also been shown to be important to the regulation of proliferation and the expression of senescence-related genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: HELLS