Western blot (WB) analysis of Smad2/3 (S2) pAb in extracts from PC12 cells. Immunohistochemistry (IHC) analyzes of Smad2/3 (S2) pAb in paraffin-embedded human colon carcinoma tissue.
55 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publication using NBP1-19520 in the following applications:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
15mM Sodium Azide
Immunogen affinity purified
Alternate Names for Smad2/3 Antibody
JV18-1SMAD, mothers against DPP homolog 2 (Drosophila)
MAD homolog 2
Mad protein homolog
Mad, mothers against decapentaplegic homolog 2
Mad-related protein 2
mother against DPP homolog 2
mothers against decapentaplegic homolog 2
Mothers against DPP homolog 2
Sma- and Mad-related protein 2
SMAD family member 2MAD, mothers against decapentaplegic homolog 2 (Drosophila)
SMAD, mothers against DPP homolog 2
Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of GFbeta/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFbeta and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFbeta signaling by interfering with TGFbeta-mediated phosphorylation of other Smad proteins.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
Review this Product
Be the first to review our Smad2/3 Antibody and receive a gift card or discount.