SLC26A7 Antibody (14H5) [DyLight 350]

Product Discontinued

SLC26A7 Antibody (14H5) [DyLight 350] Summary

• Immunogen: A fusion protein containing the C-terminal region of mouse SLC26A7. [Swiss-Prot# Q24JS8]
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: SLC26A7
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: This SLC26A7 antibody is useful for Western blot on cells transiently transfected with mouse SLC26A7 and also for Immunocytochemistry/Immunofluorescence. In WB a band can be seen at ~90-100 kDa representing SLC26A7. Note: Do not boil the samples.

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SLC26A7 Antibody (14H5) [DyLight 350]

• MGC126268
• solute carrier family 26, member 7
• sulfate anion transporter

Background

SLC26A7 is a Cl-/base exchanger expressed in the proximal tubule and thick ascending limb of the loop of Henle in the kidney. It is present in endosomes, and its targeting to the basolateral membrane is increased in hypertonicity and potassium depletion. The trafficking to the cell surface suggests novel functional upregulation of SLC26A7 in states that are associated with hypokalemia or increased medullary tonicity. SLC26A7 is thought to contribute to bicarbonate, chloride, sulfate and oxalate transport in the nephron segments.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC26A7