SLC22A13 Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

SLC22A13 Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human SLC22A13.
  
  

  Source: E. coli

  Amino Acid Sequence: WVKNHTFNLSAAEQLVLSVPLDTAGHPEPCLMFRPPPANASLQDILSHRFNETQPCDMGWEYPENRLPSLKNEFNLVCDR

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

  This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: SLC22A13
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10 - 100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-32712.

  It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

  For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

• Theoretical MW: 27 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for SLC22A13 Recombinant Protein Antigen

• OAT10
• OCTL1
• OCTL3
• ORCTL3
• ORCTL-3
• Organic cation transporter-like 3
• organic cationic transporter-like 3
• organic-cation transporter like 3
• solute carrier family 22 (organic anion transporter), member 13
• solute carrier family 22 member 13
• solute carrier family 22, member 13

Background

SLC22A13, also known as ORCTL3/OCTL1, which is a member of the organic cation/anion/zwitterion transporter family, is highly expressed in the kidney, and to a weaker extent, in the brain, heart, and intestine. A functional study of Xenopus oocytes revealed that ORCTL3 functions in the uptake of urate and nicotinate. ORCTL3 may play a role in cyclosporine A-induced hyperuricemia, because cyclosporine A enhances urate uptake by ORCTL3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: SLC22A13