SIRT7 Antibody

Immunohistochemistry-Paraffin: SIRT7 Antibody [NBP2-20375] - Paraffin-embedded mouse brain. SIRT7 antibody [N2C3] diluted at 1:400.

• Reactivity: Mu, Hu, Rt, Po, Bv, Ch, RM
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

SIRT7 Antibody Summary

• Description: Novus Biologicals Rabbit SIRT7 Antibody (NBP2-20375) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human SIRT7. The exact sequence is proprietary.
• Predicted Species: Human (100%), Rat (98%), Porcine (94%), Bovine (95%), Rhesus Macaque (99%), Chicken (90%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SIRT7
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
• Theoretical MW: 45 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 1% BSA, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for SIRT7 Antibody

• EC 3.5.1.-
• MGC126840
• MGC126842
• silent mating type information regulation 2, S.cerevisiae, homolog 7
• SIR2L7
• SIR2L7NAD-dependent deacetylase sirtuin-7
• SIR2-like protein 7
• sir2-related protein type 7
• sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
• sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 7
• Sirtuin 7
• sirtuin type 7

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: SIRT7
• Uniprot:
  • Q9NRC8(Human)