SIRP beta 1/gamma Antibody (OX117) [HRP]

• Reactivity: Hu
• Applications: ELISA, Flow, IP
• Clone: OX117
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: HRP

SIRP beta 1/gamma Antibody (OX117) [HRP] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant human SIRPgamma:CD4 fusion protein.
• Specificity: This antibody binds to human SIRP beta 1/gamma.
• Isotype: IgG Kappa
• Clonality: Monoclonal
• Host: Rabbit
• Gene: SIRPB1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for SIRP beta 1/gamma Antibody (OX117) [HRP]

• CD172 antigen-like family member B
• CD172b
• signal-regulatory protein beta-1
• SIRP beta 1/gamma
• SIRP-BETA-1

Background

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SIRPB1