Siglec-1/CD169 Antibody (ED3) [DyLight 488]

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-Fr
Clone
ED3
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Siglec-1/CD169 Antibody (ED3) [DyLight 488] Summary

Immunogen
Rat Spleen cell homogenate
Specificity
NB100-65301 recognizes the rat CD169 cell surface antigen, a 185kD molecule expressed by macrophages, predominately confined to lymphoid organs only. Monocytes and granulocytes are negative. No other cell types are positive. The most conspicious property of ED3 is it stains marginal zone macrophages and marginal metallophils in the spleen very strongly. Furthermore, macrophages in (auto-immune) diseased tissues express the ED3 antigen. In healthy tissue no expression occurs. CD169 is a receptor for glycoconjugates containing sialic acid.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
SIGLEC1
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Siglec-1/CD169 Antibody (ED3) [DyLight 488]

  • CD169
  • FLJ00051
  • sialic acid binding Ig-like lectin 1, sialoadhesin
  • sialoadhesin

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Siglec-1/CD169 Antibody (NB100-65301G) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB100-65301APC
DyLight 350 Labeled NB100-65301UV
DyLight 405 Labeled NB100-65301V
DyLight 680 Labeled NB100-65301FR
DyLight 755 Labeled NB100-65301IR
PE Labeled NB100-65301PE
PerCP Labeled NB100-65301PCP

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Bioinformatics Tool for Siglec-1/CD169 Antibody (NB100-65301G)

Discover related pathways, diseases and genes to Siglec-1/CD169 Antibody (NB100-65301G). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Siglec-1/CD169 Antibody (NB100-65301G)

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Research Areas for Siglec-1/CD169 Antibody (NB100-65301G)

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Contact Information

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Bioinformatics

Gene Symbol SIGLEC1