SIAE Antibody (03) [mFluor Violet 500 SE]

• Reactivity: Hu
• Applications: IHC
• Clone: 03
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 500 SE

SIAE Antibody (03) [mFluor Violet 500 SE] Summary

• Immunogen: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SIAE (Uniprot#: Q9HAT2-1; Met1-Lys523).
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SIAE
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SIAE Antibody (03) [mFluor Violet 500 SE]

• AIS6
• CSEC
• CSE-C
• cytosolic sialic acid 9-O-acetylesterase homolog
• EC 3.1.1.53
• H-Lse
• LSE
• MGC87009
• sialate O-acetylesterase
• sialic acid acetylesterase
• Sialic acid-specific 9-O-acetylesterase
• sialic acid-specific acetylesterase II
• Ysg2 homolog (mouse)
• YSG2

Background

Sialic acids are acidic 9-carbon sugars typically found at the nonreducing end of sugar chains. They are frequently modified by 9-O-acetylation, and this modification is removed by sialic acid acetylesterases. SIAE appears to encode both lysosomal and cytosolic sialic acid acetylesterase isoforms (LSE and CSE, respectively) (Takematsu et al., 1999 [PubMed 10464298]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SIAE