Recombinant Human Serum Amyloid A4 Protein

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SDS-Page: Serum Amyloid A4 Recombinant Protein [NBP1-50879]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Human Serum Amyloid A4 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 21-130 of Human Serum Amyloid A4

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MWRSFFKEAL QGVGDMGRAY WDIMISNHQN SNRYLYARGN YDAAQRGPGG VWAAKLISRS RVYLQGLIDY YLFGNSSTVL EDSKSNEKAE EWGRSGKDPD RFRPDGLPKK Y

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
SAA4
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
14.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol, 5mM DTT, 0.2M NaCl, 0.5mM EDTA.
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human Serum Amyloid A4 Protein

  • C-SAA
  • C-SAACSAAConstitutively expressed serum amyloid A protein
  • SAA4
  • SAA5
  • serum amyloid A-4 protein
  • Serum Amyloid A4
  • serum amyloid A4, constitutive

Background

SAA4 is a constitutively expressed protein belonging to the SAA family. It is a major acute phase reactant and an apolipoprotein of the HDL complex. SAA4 is constitutively expressed only in humans and mice, is associated almost entirely with lipoproteins of the high density range. Its physiological function is unknown and its serum concentration has no relationship with those of other major apolipoproteins. The presence of SAA4 mRNA and protein in macrophage derived foam cells of coronary and carotid arteries suggested a specific role of human SAA4 during inflammation including atherosclerosis. Recombinant human SAA4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol SAA4
Entrez