| Reactivity | HuSpecies Glossary |
| Applications | WB, IP |
| Clone | 373008 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Alexa Fluor 647 |
| Immunogen | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Serpin D1/Heparin Cofactor II Gly20-Arg498 Accession # P05546 |
| Specificity | Detects human Serpin D1/Heparin Cofactor II in direct ELISAs and Western blots. In Western blots, no cross‑reactivity with recombinant human Serpin A3, A4, B6, B8, C1, I1, I2, recombinant mouse Serpin A1, A6, D1, E1, E2, F1, or F2 is observed. |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Host | Mouse |
| Purity Statement | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Storage | Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied |
| Buffer | Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide |
Serpin D1, also known as Heparin Cofactor II, is a member of the Serpin superfamily of the serine protease inhibitors (1). Similar to Serpins A5 and C1, it inhibits thrombin and this activity is enhanced by heparin. Interestingly, a C-terminal His-tagged recombinant Serpin D1 had enhanced heparin effect, which was maintained in a plasma-based thrombin inhibition assay (2). Congenital Serpin D1 deficiency is a potential risk factor for thrombosis (3).
![Serpin D1/Heparin Cofactor II Antibody (373008) [Alexa Fluor® 647]](/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png "Serpin D1/Heparin Cofactor II Antibody (373008) [Alexa Fluor® 647]")
Secondary Antibodies |
Isotype Controls |
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