SCGB1D2 Antibody

• Reactivity: Hu
• Applications: ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

SCGB1D2 Antibody Summary

• Description: Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.
• Immunogen: Peptide with sequence CTDQMSLQKRSLIAE corresponding to internal region according to NP_006542.1.
• Epitope: CTDQMSLQKRSLIAE
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SCGB1D2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
• Application Notes: WB: Not yet tested - Our standard WB protocol would not expect to reliably detect proteins as small as the calculated size of 9.9 kDa band according to NP_006542.1.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SCGB1D2 Antibody

• LIPB
• LIPHB
• lipophilin-B
• LPHB
• prostatein-like lipophilin B
• secretoglobin family 1D member 2
• secretoglobin, family 1D, member 2

Background

The protein encoded by the SCGB1D2 gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SCGB1D2 Antibody (NBP1-06048)(1)

Publication using NBP1-06048

• Carter D, Dillon DC, Reynolds LD et al. Serum antibodies to lipophilin B detected in late stage breast cancer patients. Clin Cancer Res 2003-02-01 [PMID: 12576445]

Bioinformatics

• Gene Symbol: SCGB1D2
• Entrez:
  • 10647(Human)
• Uniprot:
  • NP_006542.1(Human)